R&D Service


From drug discovery to commercialization of the "one-stop" service platform

New Drug Preclinical Research Service

Caremo has established an animal model repository encompassing disease models across therapeutic areas including:

- Oncology
- Cardiovascular & cerebrovascular diseases
- Respiratory disorders
- Gastrointestinal pathologies

 

This continuously expanding collection enables customized development of validated preclinical models tailored to client-specific requirements, supporting pharmacological and efficacy evaluations for novel drug candidates.

Tumor disease models Digestive system disease models Cardiovascular and cerebrovascular disease models Respiratory disease models
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· CDX models

· Syngeneic mouse models

· Orthotopic tumor models

· Humanized mouse models

· PDX models etc

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· Gastric ulcer models

· Anemia models

· Colitis models, etc

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· Myocardial infarct models

· Stroke models

· Aortic dissection models

· Hypertension models

· Heart failure models, etc

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· Pulmonary fibrosis models

· Acute lung injury models

· Pulmonary edema models, etc

Service Advantages

High level team formed by the core of well-known pharmacology and pharmacodynamics experts

Caremo has built a rigorous and excellent research team,the core members are composed of experienced biology expert, returnee pharmacologist and professionals with doctoral backgrounds from well-known universities. Also, our core technicians are from eminent companies with professional laboratory management experience.

FTE and FFS, two efficient business models in parallel

The customized projects can be completed quickly with high success rate, and the project teams are very experienced, we can effectively meet the different needs of companies at different stages for compound synthesis.

Comprehensive and advanced equipment and data management system

We have a 11000+㎡ research center, including 2500㎡ new drug preclinical research laboratory (including P2 lab), fully equipped with advanced equipment and digital data management system, and we have CNAS quality management system, and introducing advanced GLP management concept. The experimental operations are strictly complied with ICH and NMPA guidelines to ensure the efficient operation of the whole process of the laboratory, and able to conduct multiple animal experiments at the same time and ensure the integrity and accuracy of experiments data.

PROTAC target protein degradation test

Caremo can detect the target of PROTAC drugs. PROTAC action mechanism is distinguished from traditional drugs which are relied on binding of molecules and target proteins. PROTAC mainly depends on the proximity of E3 ligase and target protein, thereby to degrade the target protein, The drug is evaluated through the detection of cell level and protein level.

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