R&D Service
From drug discovery to commercialization of the "one-stop" service platform
New Drug Preclinical Research Service
Caremo maintains standardized laboratories equipped with advanced chemical synthesis and analytical equipment, enabling the delivery of FTE (Full-Time Equivalent) and FFS (Fee-for-Service) models to pharmaceutical companies and research institutions worldwide. Our services encompass:
- Medicinal chemistry
- Structural biochemistry platforms
- Computational biology and molecular modeling
- Custom synthesis and scale-up synthesis
- Novel drug development technologies
By leveraging extensive expertise in chemical synthesis, medicinal chemistry, and analytical chemistry, coupled with rigorous project management and a robust feedback mechanism, Caremo provides consistent, high-quality services while actively safeguarding client intellectual property rights and ensuring data integrity throughout all collaborations.
· Synthesis of SAR-based compounds
· Synthesis of small molecule compound libraries
· Synthesis of hit compounds
· SAR studies
· Synthesis\discovery\structure optimization of hit compounds
· On time delivery ≥ 90%
· Per full-time-employee (FTE) delivers 1 compound each week
· Completed reactions per person per week≥ 10
· Chemical reactions success rate≥ 85%
· Strict project management and feedback mechanism
· Synthesis of high-quality kilogram-level samples
· Synthetic technique studies of target compounds
· CDMO for ton-level API or intermediates
· Protein degradation technology (PROTAC Technology)
· Cyclic peptide synthesis technology
· PDC/ADC drug R&D technology
· Bioisostere technology
· Green chemical synthesis technology
Service Advantages
High level team formed by the core of well-known pharmacology and pharmacodynamics experts
Caremo has built a rigorous and excellent research team，the core members are composed of experienced biology expert, returnee pharmacologist and professionals with doctoral backgrounds from well-known universities. Also, our core technicians are from eminent companies with professional laboratory management experience.
FTE and FFS, two efficient business models in parallel
The customized projects can be completed quickly with high success rate, and the project teams are very experienced, we can effectively meet the different needs of companies at different stages for compound synthesis.
Comprehensive and advanced equipment and data management system
We have a 10000+㎡ research center, including 2500㎡ new drug preclinical research laboratory (including P2 lab), fully equipped with advanced equipment and digital data management system, and we have CNAS quality management system, and introducing advanced GLP management concept. The experimental operations are strictly complied with ICH and NMPA guidelines to ensure the efficient operation of the whole process of the laboratory, and able to conduct multiple animal experiments at the same time and ensure the integrity and accuracy of experiments data.
PROTAC target protein degradation test
Caremo can detect the target of PROTAC drugs. PROTAC action mechanism is distinguished from traditional drugs which are relied on binding of molecules and target proteins. PROTAC mainly depends on the proximity of E3 ligase and target protein, thereby to degrade the target protein, The drug is evaluated through the detection of cell level and protein level.
Follow us
Contract Us：
Add：Building C6, No. 9, Weidi Road, Qixia District, Nanjing
P.C：210046
Tel：025-85760569
M.P：bd@caremo.com.cn
